{"id":2315,"date":"2025-12-29T16:21:33","date_gmt":"2025-12-29T07:21:33","guid":{"rendered":"https:\/\/beyondlife.kr\/?p=2315"},"modified":"2025-12-29T16:21:33","modified_gmt":"2025-12-29T07:21:33","slug":"%ec%a0%8a%ec%9d%8c%ec%9d%84-%ec%82%ac%eb%8a%94-%ec%84%b8%ec%83%81","status":"publish","type":"post","link":"https:\/\/beyondlife.kr\/?p=2315","title":{"rendered":"\uc80a\uc74c\uc744 \uc0ac\ub294 \uc138\uc0c1"},"content":{"rendered":"

\ubaa8\ub4e0 \uc774\uac00 \ub299\ub294\ub2e4\ub294 \uc6b4\uba85\ub860\uc740 \uc61b\ub9d0\uc774\ub2e4. \ub178\ud654\ub97c \uc5ed\ud589\ud558\uace0, \uc80a\uc74c\uc744 \ub3c8\uc73c\ub85c \uc0b4 \uc218 \uc788\ub2e4\ub294 \uac00\ub2a5\uc131\uc774 \uc5b8\uae09\ub418\uba74\uc11c \uc778\ub958\uc758 \uc0c1\uc2dd\uc744 \ub4a4\uc5ce\uc5c8\ub2e4.<\/p><\/blockquote>\n\n\n\n
\"\uc80a\uc74c\uc744<\/p>\n

\u24d2 shutterstock<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\uc80a\uc74c\uc744 \ud5a5\ud55c \uac08\ub9dd\uacfc \ub178\ud654\uc5d0 \ub300\ud55c \uacf5\ud3ec. \uc740\ud1f4\ud55c 50\uc138 \uc804\uc9c1 \uc2a4\ud0c0\uac00 \uc2e0\ube44\ub85c\uc6b4 \uc2e0\uc57d\uc73c\ub85c \uc80a\uc74c\uc744 \ub418\ucc3e\ub294\ub2e4. \uc601\ud654 <\uc11c\ube0c\uc2a4\ud134\uc2a4>\ub294 \uc778\uac04\uc758 \uac00\uc7a5 \uc6d0\ucd08\uc801\uc778 \uc695\ub9dd\uc744 \uadf8\ub85c\ud14c\uc2a4\ud06c\ud558\uac8c \ud480\uc5b4\ub0b8\ub2e4. \ubb3c\ub860 \uc774\uc57c\uae30\ub294 \uc601\ud654\uc801 \ud5c8\uad6c\ub2e4. \ud558\uc9c0\ub9cc \uc601\ud654\uac00 \ub358\uc9c0\ub294 \uc9c8\ubb38\uc740 \ub354 \uc774\uc0c1 \uacf5\uc0c1 \uacfc\ud559 \uc601\uc5ed\uc5d0\ub9cc \uba38\ubb3c\uc9c0 \uc54a\ub294\ub2e4. \ub178\ud654\ub294 \uc5b4\uca4c\uba74, \ud53c\ud560 \uc218 \uc5c6\ub294 \uc6b4\uba85\uc774 \uc544\ub2d0\uc9c0\ub3c4 \ubaa8\ub978\ub2e4.<\/p>\n

\uc800\uc18d\ub178\ud654, \uc2dc\ub300\uc758 \ud654\ub450\uac00 \ub418\ub2e4<\/h3>\n

\u2018\uc800\uc18d\ub178\ud654\u2019, \ucd5c\uadfc \uba87 \ub144 \uc0ac\uc774 \ud55c\uad6d \uc0ac\ud68c\ub97c \uad00\ud1b5\ud558\ub294 \ud0a4\uc6cc\ub4dc\ub2e4. \ub2e8\uc21c\ud55c \uc720\ud589\uc744 \ub118\uc5b4 \ud558\ub098\uc758 \ubb38\ud654\ud604\uc0c1\uc774 \ub418\uc5c8\ub2e4. MZ\uc138\ub300\ubd80\ud130 \uc911\uc7a5\ub144\uce35\uae4c\uc9c0, \uc138\ub300\ub97c \ub9c9\ub860\ud558\uace0 \uc0ac\ub78c\ub4e4\uc740 \ub354 \uc774\uc0c1 \uc624\ub798 \uc0ac\ub294 \uac83\ub9cc\uc744 \ubaa9\ud45c\ub85c \ud558\uc9c0 \uc54a\ub294\ub2e4. \uac74\uac15\ud558\uac8c \uc624\ub798 \uc0b4\uae30. \uadf8\ub9ac\uace0 \ubb34\uc5c7\ubcf4\ub2e4 \u2018\uc80a\uac8c \ub299\ub294 \uac83\u2019\uc5d0 \uad00\uc2ec\uc744 \uc3df\ub294\ub2e4.<\/p>\n

\uc720\ud29c\ube0c\ub098 \ube14\ub85c\uadf8 \ub4f1 \uc628\ub77c\uc778 \ubbf8\ub514\uc5b4\uc5d0\ub294 \u2018\uc800\uc18d\ub178\ud654 \ub8e8\ud2f4\u2019, \u2018\uc800\uc18d\ub178\ud654 \uc2dd\ub2e8\u2019 \uac19\uc740 \uc790\uae30 \uad00\ub9ac \ucf58\ud150\uce20\uac00 \ubd07\ubb3c\uc744 \uc774\ub8ec\ub2e4. \uadf8 \ud750\ub984\uc5d0\ub530\ub77c \uc0ac\ub78c\ub4e4\uc758 \uc18c\ube44 \uc2b5\uad00\ub3c4 \ubcc0\ud654\ud55c\ub2e4. \ud770\uc300\ubc25 \ub300\uc2e0 \uc7a1\uace1\ubc25\uc744,\uc77c\ubc18 \uc2dd\uc6a9\uc720 \ub300\uc2e0 \uc5d1\uc2a4\ud2b8\ub77c\ubc84\uc9c4 \uc62c\ub9ac\ube0c\uc624\uc77c\uc744 \uace0\ub974\ub294 \uac74 \uc774\uc81c\ud2b9\ubcc4\ud55c \uc120\ud0dd\uc774 \uc544\ub2c8\ub2e4. \uac04\ud5d0\uc801 \ub2e8\uc2dd, \uc800\ub2f9 \uac04\uc2dd, \ud56d\uc0b0\ud654 \uc2dd\ud488\uc740\uac74\uac15 \ub9c8\ub2c8\uc544\uce35\uc744 \ub118\uc5b4 \ubaa8\ub4e0 \uc774\uc758 \uc77c\uc0c1\uc774 \ub418\uc5c8\ub2e4.<\/p>\n

\uc774 \ud750\ub984\uc740 \uc2dd\ud488\uacfc \uac74\uac15\uae30\ub2a5\uc2dd\ud488 \uc0b0\uc5c5\uc5d0\ub3c4 \ub69c\ub837\ud55c \ubcc0\ud654\ub97c \ubd88\ub7ec\uc654\ub2e4. \uae30\uc874\uc758 \ubcf4\ucda9\uc81c \uc911\uc2ec \uc2dc\uc7a5\uc5d0\uc11c \ubc97\uc5b4\ub098 \ud56d\uc0b0\ud654 \uc791\uc6a9\uacfc \ub178\ud654 \ubc29\uc9c0\ub97c \ub0b4\uc138\uc6b4 \uace0\uae30\ub2a5\uc131 \uc81c\ud488\uc774 \uc8fc\ubaa9\ubc1b\uace0 \uc2dd\ubb3c\uc131 \uc6d0\ub8cc, \uc7a5\ub0b4\ubbf8\uc0dd\ubb3c \uae30\ubc18 \uc194\ub8e8\uc158, \uc720\uc804\uc790 \ubd84\uc11d\uc744 \ud65c\uc6a9\ud55c \ub9de\ucda4\ud615 \uc81c\ud488\uad70\uc774 \uc0c8\ub85c\uc6b4 \uc131\uc7a5\ucd95\uc73c\ub85c \ubd80\uc0c1\ud588\ub2e4.<\/p>\n

\uc8fc\ubaa9\ud560 \uc810\uc740 \uc774 \ubaa8\ub4e0 \ubcc0\ud654\uc758 \ubc14\ud0d5\uc5d0 \ub178\ud654\uc5d0 \ub300\ud55c \uc778\uc2dd \uc804\ud658\uc774\uc790\ub9ac\ud55c\ub2e4\ub294 \uc0ac\uc2e4\uc774\ub2e4. \ub178\ud654\ub294 \ub354 \uc774\uc0c1 \ud53c\ud560 \uc218 \uc5c6\ub294 \uc219\uba85\uc774 \uc544\ub2c8\ub2e4. \uad00\ub9ac\ud560 \uc218 \uc788\ub2e4. \ub2a6\ucd9c \uc218 \uc788\ub2e4. \uc5b4\uca4c\uba74 \ub418\ub3cc\ub9b4 \uc218\ub3c4 \uc788\ub2e4.\uc774\uac83\uc774 \ubc14\ub85c \uc6b0\ub9ac\uac00 \ub178\ud654\ub97c \ubc14\ub77c\ubcf4\ub294 \uc0c8\ub85c\uc6b4 \uc2dc\uc120\uc774\ub2e4.<\/p>\n

\ubcd1\uc774 \ub41c \ub178\ud654<\/h3>\n

\ud558\ubc84\ub4dc\ub300\ud559\uad50 \uc758\uacfc\ub300\ud559 \uc720\uc804\ud559\uc790 \ub370\uc774\ube44\ub4dc \uc2f1\ud074\ub808\uc5b4 \uad50\uc218\ub294 2019\ub144 \ucd9c\uac04\ud55c \uc800\uc11c <\ub178\ud654\uc758 \uc885\ub9d0(Lifespan)>\ub97c \ud1b5\ud574 \ub178\ud654\ub97c \ud53c\ud560 \uc218 \uc5c6\ub294 \uc790\uc5f0\ud604\uc0c1\uc774 \uc544\ub2cc \uacfc\ud559\uc73c\ub85c \uac1c\uc785 \uac00\ub2a5\ud558\uace0 \uce58\ub8cc \uac00\ub2a5\ud55c \u2018\uc9c8\ubcd1\u2019\uc73c\ub85c \uc815\uc758\ud55c\ub2e4.<\/p>\n

\uc774 \uc8fc\uc7a5\uc740 \ub2e8\uc21c\ud55c \ucca0\ud559\uc758 \ub3c4\ubc1c\uc774 \uc544\ub2c8\ub2e4. \uc2f1\ud074\ub808\uc5b4\ub294 \ub178\ud654\uc758 \ubd84\uc790 \uba54\ucee4\ub2c8\uc998\uc744 \uc5f0\uad6c\ud558\ub294 \uc138\uacc4\uc801 \uc720\uc804\uccb4\ud559\uc790\ub2e4. \uadf8\ub294 \uc218\uc2ed \ub144\uac04 NAD+ \ub300\uc0ac, \uc2dc\ub974\ud22c\uc778 \ub2e8\ubc31\uc9c8, \uc5fc\uc0c9\uc9c8 \uc548\uc815\uc131 \ub4f1 \uc138\ud3ec \uc218\uc900\uc758 \ub178\ud654 \uacfc\uc815\uc744 \uaddc\uba85\ud558\ub294 \ub370 \uc55e\uc7a5\uc130\ub2e4. \uc774\ub860\ub9cc \uc81c\uc2dc\ud558\ub294 \ub370 \uadf8\uce58\uc9c0 \uc54a\uc558\ub2e4. \uc790\uc2e0\uc774 \ubcf5\uc6a9 \uc911\uc778 \ubcf4\ucda9\uc81c \ubaa9\ub85d\uacfc \uc0dd\ubb3c\ud559\uc801 \ub098\uc774 \uce21\uc815 \uacb0\uacfc\ub97c \uacf5\uac1c\ud588\ub2e4. \uadf8\ub294 \uc790\uc2e0\uc758 \uc0dd\ubb3c\ud559\uc801 \ub098\uc774\uac00 \uc2e4\uc81c\ubcf4\ub2e4 10\ub144 \uc774\uc0c1 \uc80a\ub2e4\uace0 \uc8fc\uc7a5\ud588\ub2e4.<\/p>\n

\uc774 \ubc1c\uc5b8\uc740 \uacfc\ud559\uacc4\uc640 \ub300\uc911 \uc0ac\uc774\uc5d0 \ub17c\uc7c1\uacfc \ud68c\uc758, \uae30\ub300\ub97c \ub3d9\uc2dc\uc5d0 \ubd88\ub7ec\uc77c\uc73c\ucf30\ub2e4. \uc9c0\ub09c \uc218\ucc9c \ub144\uac04 \uc778\ub958\ub294 \ub178\ud654\ub97c \uc219\uba85\uc73c\ub85c \ubc1b\uc544\ub4e4\uc600\ub2e4. \ud558\uc9c0\ub9cc \uc2f1\ud074\ub808\uc5b4\ub97c \ube44\ub86f\ud55c \uc0c8\ub85c\uc6b4 \uc138\ub300 \uacfc\ud559\uc790\ub294 \ubb3b\ub294\ub2e4. \uc65c \uc6b0\ub9ac\ub294 \ub299\uc5b4\uc57c \ud558\ub294\uac00? \uadf8\ub9ac\uace0 \uc815\ub9d0 \uadf8\ub798\uc57c\ub9cc \ud558\ub294\uac00?<\/p>\n\n\n\n
\"\ub370\uc774\ube44\ub4dc<\/p>\n

\ub370\uc774\ube44\ub4dc \uc2f1\ud074\ub808\uc5b4 \uad50\uc218\uc758 \uac15\uc5f0. \uadf8\uc758 \ub4a4\uc5d0 \u2018\ub9cc\uc57d \ub178\ud654\uac00 \uc9c8\ubcd1\uc774\uace0, \uadf8 \uc9c8\ubcd1\uc774 \uce58\ub8cc \uac00\ub2a5\ud558\ub2e4\uba74?\u2019 \uc774\ub77c \uc368 \uc788\ub2e4.\u00a0\u24d2 davidsinclairphd \ub299\uc5b4\uc57c\ub9cc \ud55c\ub2e4\ub294 \uc0dd\ubb3c\ud559\uc801 \ubc95\uce59\uc740 \uc5c6\ub2e4. \u2013<\ub178\ud654\uc758 \uc885\ub9d0> \uc911<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\ub178\ud654\ub294 \u2018CD\uc5d0 \ub09c \ud760\uc9d1\u2019<\/h3>\n

\uc2f1\ud074\ub808\uc5b4\uc5d0 \ub530\ub974\uba74, \ub178\ud654\ub294 \uc138\ud3ec\uac00 \uc790\uc2e0\uc758 \uae30\ub2a5\uc744 \uc810\ucc28 \uc783\uc5b4\uac00\ub294 \uacfc\uc815\uc774\ub2e4. \uc774\ub97c \uc124\uba85\ud558\uae30 \uc704\ud574 \uadf8\ub294 \uc138\ud3ec \uc18d DNA\ub97c \uc74c\uc545\uc774 \ub2f4\uae34 CD\uc5d0 \ube44\uc720\ud55c\ub2e4. \ucc98\uc74c\uc5d4 \uc644\ubcbd\ud558\uac8c \uc791\ub3d9\ud558\ub358 CD\ub3c4 \uc2dc\uac04\uc774 \uc9c0\ub098\uba70 \ud45c\uba74\uc5d0 \ud760\uc9d1\uc774 \uc0dd\uae34\ub2e4. \uc7ac\uc0dd \uc7a5\uce58\uac00 \uc815\ubcf4\ub97c \uc81c\ub300\ub85c \uc77d\uc9c0 \ubabb\ud55c\ub2e4. \uc74c\uc545\uc774 \ud750\ud2b8\ub7ec\uc9c4\ub2e4. \uace1\uc740 \uadf8\ub300\ub85c \uc874\uc7ac\ud55c\ub2e4. \ud558\uc9c0\ub9cc \uc5f0\uc8fc\uac00 \ub354 \uc774\uc0c1 \uc6d0\ub798\ucc98\ub7fc \ub4e4\ub9ac\uc9c0 \uc54a\ub294\ub2e4.<\/p>\n

DNA \uc5fc\uae30\uc11c\uc5f4 \uc790\uccb4\ub294 \ubcc0\ud558\uc9c0 \uc54a\ub294\ub2e4. \ud558\uc9c0\ub9cc \uc720\uc804\uc790\ubc1c\ud604\uc744 \uc870\uc808\ud558\ub294 \ud6c4\uc131\uc720\uc804\ud559 \ud45c\uc9c0(EpigeneticMarkers)\uac00 \uc190\uc0c1\ub418\uba74, \uc138\ud3ec\ub294 \ubcf8\ub798 \uae30\ub2a5\uc744 \uc218\ud589\ud558\uc9c0 \ubabb\ud55c\ub2e4. \uc2f1\ud074\ub808\uc5b4\ub294 \uc774 \ud604\uc0c1\uc744 \u2018\ud6c4\uc131\uc720\uc804\ud559 \uc815\ubcf4\uc758 \uc0c1\uc2e4(Epigenetic Information Loss)\u2019\uc774\ub77c \ubd80\ub978\ub2e4.<\/p>\n

\uc774\ub97c \ubc14\ud0d5\uc73c\ub85c \u2018\ub178\ud654\uc758 \uc815\ubcf4 \uc774\ub860(InformationTheory of Aging)\u2019\uc744 \uc81c\uc2dc\ud588\ub2e4. \ud575\uc2ec\uc740 \uac04\ub2e8\ud558\ub2e4.\ub3cc\uc5f0\ubcc0\uc774\ub098 \ud154\ub85c\ubbf8\uc5b4 \ub2e8\ucd95\ubcf4\ub2e4 \uc138\ud3ec\uac00 \uc790\uc2e0\uc758 \uc815\uccb4\uc131\uacfc \uae30\ub2a5\uc5d0 \ub300\ud55c \u2018\uc815\ubcf4\u2019\ub97c \uc778\uc2dd\ud558\uace0 \ud574\uc11d\ud558\ub294 \ub2a5\ub825\uc774 \uc810\uc810 \ud750\ub824\uc9c4\ub2e4\ub294 \uac83\uc774\ub2e4.<\/p>\n

\uc774 \uc774\ub860\uc740 \uc2e4\ud5d8\uc744 \ud1b5\ud574 \uc77c\uc815 \ubd80\ubd84 \uc785\uc99d\ub418\uc5c8\ub2e4. \uc2f1\ud074\ub808\uc5b4 \uc5f0\uad6c\ud300\uc740 \uc80a\uc740 \uc0dd\uc950\uc758 DNA\uc5d0 \uc778\uc704\ub85c \uc190\uc0c1\uc744 \uac00\ud588\ub2e4. \uc5fc\uae30\uc11c\uc5f4\uc740 \uadf8\ub300\ub85c\uc778 \uc0c1\ud0dc\uc600\ub2e4. \uadf8\ub7f0\ub370 \uc0dd\uc950\ub294 \uae09\uc18d\ud55c \ub178\ud654 \uc9d5\ud6c4\ub97c \ubcf4\uc600\ub2e4. \ud138\uc774 \ud76c\uc5b4\uc9c0\uace0, \uc7a5\uae30\uae30\ub2a5\uc774 \uc800\ud558\ub410\ub2e4. \uc870\uc9c1 \ub0b4\uc5d0\ub294 \ub178\ud654 \uad00\ub828 \uc138\ud3ec\uac00 \ub2e4\uc218 \ubc1c\uacac\ub418\uc5c8\ub2e4. \ud6c4\uc131\uc720\uc804\ud559 \uc815\ubcf4\ub9cc \uad50\ub780\ud574\ub3c4 \ub178\ud654\uac00 \uc720\ub3c4\ub420 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubcf4\uc5ec \uc900 \uac83\uc774\ub2e4. \ub178\ud654\uac00 \ub2e8\uc21c\ud55c \uc138\ud3ec \ub9c8\ubaa8\ub098 \uc720\uc804\uc790 \uc190\uc0c1 \ucd95\uc801\uc774 \uc544\ub2c8\ub77c\ub294 \ub73b\uc774\ub2e4. \uc138\ud3ec \ub0b4 \uc815\ubcf4 \uc2dc\uc2a4\ud15c\uc758 \ubd95\uad34\uc77c \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud55c\ub2e4.<\/p>\n

\uc2dc\uac04\uc744 \ub418\ub3cc\ub9b0 \uc2e4\ud5d8\uc2e4\uc758 \uae30\uc801<\/h3>\n

\uadf8\ub807\ub2e4\uba74 \ub178\ud654\ub97c \ub418\ub3cc\ub9b4 \ubc29\ubc95\uc740 \ubb34\uc5c7\uc77c\uae4c? \uc2f1\ud074\ub808\uc5b4\ub294 \uc774\ub97c \uac00\ub2a5\ud558\uac8c \ud558\ub294 \ud574\ubc95\uc73c\ub85c \u2018\uc138\ud3ec \ub9ac\ud504\ub85c\uadf8\ub798\ubc0d(Cellular Reprogramming)\u2019\uc744 \uc81c\uc2dc\ud55c\ub2e4. \ucef4\ud4e8\ud130\ub97c \ucd08\uae30\ud654\ud558\ub4ef, \uc138\ud3ec\uc758 \uc0dd\ubb3c\ud559 \uc2dc\uacc4\ub97c \uc80a\uc740 \uc0c1\ud0dc\ub85c \ub418\ub3cc\ub9ac\ub294 \uae30\uc220\uc774\ub2e4.<\/p>\n

\uae30\uc220\uc758 \ud575\uc2ec\uc740 \u2018\uc57c\ub9c8\ub098\uce74 \uc778\uc790(Yamanaka Factors)\u2019\ub2e4. 2006\ub144, \uad50\ud1a0\ub300\ud559\uad50 \uc57c\ub9c8\ub098\uce74 \uc2e0\uc57c \uad50\uc218\ub294 \uc131\uccb4\uc138\ud3ec\ub97c \uc904\uae30\uc138\ud3ec \uc0c1\ud0dc\ub85c \ub418\ub3cc\ub9ac\ub294 \ub124 \uac00\uc9c0 \uc804\uc0ac\uc778\uc790\ub97c \ubc1c\uacac\ud588\ub2e4. Oct4, Sox2, Klf4, c-Myc. \ud53c\ubd80\uc138\ud3ec\ub97c \ucd08\uae30 \ubc30\uc544 \ub2e8\uacc4\ucc98\ub7fc \u2018\ub9ac\uc14b\u2019\ud560 \uc218 \uc788\uc5c8\ub2e4. \uc774 \ubc1c\uacac\uc740 \uc0dd\ubb3c\ud559\uacc4\uc5d0 \ucda9\uaca9\uc744 \uc548\uacbc\ub2e4. \uc57c\ub9c8\ub098\uce74\ub294 2012\ub144\u00a0\ub178\ubca8 \uc0dd\ub9ac\uc758\ud559\uc0c1\uc744 \ubc1b\uc558\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \uc774 \uae30\uc220\uc5d0\ub294 \uce58\uba85\uc801 \ud55c\uacc4\uac00 \uc788\uc5c8\ub2e4. \ub124 \uc778\uc790\ub97c \ubaa8\ub450 \uc0ac\uc6a9\ud558\uba74 \uc138\ud3ec\uac00 \uacfc\ub3c4\ud558\uac8c \uc80a\uc5b4\uc9c4\ub2e4. \uc554\uc138\ud3ec\ucc98\ub7fc \ubcc0\ud615\ub420 \uc704\ud5d8\uc774 \uc788\uc5c8\ub358 \uac83\uc774\ub2e4. \uc2f1\ud074\ub808\uc5b4\ub294 \uc774 \ubb38\uc81c\ub97c \ud574\uacb0\ud558\uae30 \uc704\ud574 \uac00\uc7a5 \uc704\ud5d8\ud55c \uc778\uc790\uc778 c-Myc\ub97c \uc81c\uac70\ud588\ub2e4.<\/p>\n

\ub098\uba38\uc9c0 \uc138 \uc778\uc790(Oct4, Sox2, Klf4)\ub9cc \uc9e7\uc740 \uc2dc\uac04 \ub3d9\uc548 \uc791\ub3d9\uc2dc\ud0a4\ub294 \ubc29\ubc95\uc744 \uace0\uc548\ud588\ub2e4. \uc138\ud3ec\ub97c \uc644\uc804\ud788 \ucd08\uae30\ud654\ud558\uc9c0 \uc54a\uace0, \uc77c\ubd80\ubd84\ub9cc \ub418\uac10\ub294 \ubc29\uc2dd\uc774\ub2e4. \uc774\ub978\ubc14 \u2018\ubd80\ubd84 \ub9ac\ud504\ub85c\uadf8\ub798\ubc0d(Partial Reprogramming)\u2019\uc774\ub2e4.<\/p>\n

2020\ub144, \uc2f1\ud074\ub808\uc5b4 \uc5f0\uad6c\ud300\uc740 \uc774 \uc2e4\ud5d8\uc758 \uc131\uacfc\ub97c \ud559\uc220\uc9c0 <\ub124\uc774\ucc98>\uc5d0 \ubc1c\ud45c\ud588\ub2e4. \ub178\ud654\ub85c \uc2dc\ub825\uc744 \uc783\uc740 \uc950\uc5d0 \uc138 \uc720\uc804\uc790\ub97c \uc8fc\uc785\ud588\ub2e4.\u00a0 \uc190\uc0c1\ub41c \uc2dc\uc2e0\uacbd\uc138\ud3ec\uac00 \uc7ac\uc0dd\ub418\uba70 \uc2dc\ub825\uc774 \ud68c\ubcf5\ub418\ub294 \uac83\uc744 \uad00\ucc30\ud588\ub2e4. \ub2e8\uc21c\ud788 \ub178\ud654\ub97c \u2018\uc9c0\uc5f0\u2019\uc2dc\ud0a8 \uac83\uc774 \uc544\ub2c8\ub2e4.<\/p>\n

\uc774\ubbf8 \ub299\uc740 \uc138\ud3ec\uac00 \uc80a\uc740 \uc0c1\ud0dc\ub85c \u2018\ub418\ub3cc\uc544\uac04\u2019 \uccab \ubc88\uc9f8 \uc0ac\ub840\ub85c \ud3c9\uac00\ub41c\ub2e4. \ub354 \ub180\ub77c\uc6b4 \uc810\uc740 \uc774\ub807\uac8c \ud68c\ucd98\ud55c \uc138\ud3ec\ub4e4\uc774 \uc790\uc2e0\uc758 \uc815\uccb4\uc131\uc744 \uc783\uc9c0 \uc54a\uc558\ub2e4\ub294 \uac83\uc774\ub2e4. \uc2e0\uacbd\uc138\ud3ec\ub294 \uc5ec\uc804\ud788 \uc2e0\uacbd\uc138\ud3ec\ub85c, \ub9dd\ub9c9\uc138\ud3ec\ub294 \ub9dd\ub9c9\uc138\ud3ec\ub85c \uae30\ub2a5\ud588\ub2e4. \uc989 \uc138\ud3ec\uac00 \uc904\uae30\uc138\ud3ec\ub85c \ucd08\uae30\ud654\ub418\uc9c0 \uc54a\uc558\ub2e4. \ubcf8\ub798 \uc5ed\ud560\uc740 \uc720\uc9c0\ud55c \ucc44 \uc0dd\ubb3c\ud559 \uc2dc\uacc4\ub9cc \ub418\uac10\uae34 \uc148\uc774\ub2e4.<\/p>\n

\uc774 \uc2e4\ud5d8\uc740 \ub178\ud654\ub97c \ub418\ub3cc\ub9b4 \uc218 \uc788\ub294 \uc0dd\ubb3c\ud559 \uac00\ub2a5\uc131\uc744 \uc2e4\ud5d8\uc744 \ud1b5\ud574 \ucc98\uc74c \uc785\uc99d\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \uc758\ubbf8\uac00 \ud06c\ub2e4. \ub178\ud654\ub294 \ud53c\ud560 \uc218 \uc5c6\ub294 \uc219\uba85\uc774 \uc544\ub2c8\ub77c \uc870\uc808 \uac00\ub2a5\ud55c \uc0dd\ubb3c\ud559 \uacfc\uc815\uc77c \uc218 \uc788\ub2e4\ub294 \uc0c8\ub85c\uc6b4 \uc2dc\uc120\uc744 \uc5f4\uc5b4\uc900 \uac83\uc774\ub2e4. \ubb3c\ub860 \uc774 \uc5f0\uad6c\ub294 \uc544\uc9c1 \ucd08\uae30 \ub2e8\uacc4\ub2e4. \uc2e0\uc911\ud55c \ud574\uc11d\uc774 \ud544\uc694\ud558\ub2e4.<\/p>\n

\uc774\uc640 \uad00\ub828\ud574 \uac00\ucc9c\ub300\ud559\uad50 \uae38\ubcd1\uc6d0 \uac00\uc815\uc758\ud559\uacfc \uc11c\ud76c\uc120 \uad50\uc218\ub294 \u201c\uc544\uc9c1\uc740 \ub3d9\ubb3c\uc2e4\ud5d8 \ub2e8\uacc4\ub2e4. \uc124\uacc4\ub3c4\ub9cc \uc788\ub2e4\uace0\u00a0\uc9d1\uc774 \uc800\uc808\ub85c \uc9c0\uc5b4\uc9c0\uc9c0 \uc54a\ub4ef, \uc720\uc804\uc790\ub97c \uc8fc\uc785\ud55c\ub2e4\uace0 \ud574\uc11c \ubc14\ub85c \ud6a8\uacfc\uac00 \ub098\ud0c0\ub098\ub294 \uac74 \uc544\ub2c8\ub2e4\u201d\ub77c\uba70 \u201c\ub9ce\uc740 \ubcc0\uc218\uac00 \uc874\uc7ac\ud558\ub294 \ub9cc\ud07c \uc2e4\uc81c \uce58\ub8cc\ub85c \uc774\uc5b4\uc9c0\uae30\uae4c\uc9c0\ub294 \uadf9\ubcf5\ud574\uc57c \ud560 \uacfc\uc81c\uac00 \uc0b0\uc801\ud574 \uc788\ub2e4\u201d\ub77c\uace0 \uc804\ud588\ub2e4.<\/p>\n

\n

\uc138\uacc4 \uac01\uad6d\uc758 \uc5f0\uad6c\uc9c4\uc774 \uc138\ud3ec\uc758 \uc0dd\ubb3c\ud559 \uc2dc\uacc4\ub97c<\/p>\n

\ub418\uac10\uae30 \uc704\ud574 \uc2dc\ud589\ucc29\uc624\ub97c \uacaa\uace0 \uc788\ub2e4.<\/p>\n

\uc544\uc9c1 \uac08 \uae38\uc740 \uba40\uc9c0\ub9cc, \u2018\ub299\ub294\ub2e4\ub294 \uac83\u2019\uc758 \uc758\ubbf8\ub294 \ubd84\uba85\ud788 \ub2ec\ub77c\uc9c0\uace0 \uc788\ub2e4.<\/p>\n<\/blockquote>\n

\uc2e4\ud5d8\uc2e4\uc744 \ub118\uc5b4 \uc784\uc0c1\uc73c\ub85c<\/h3>\n

\ub178\ud654\ub97c \uc870\uc808 \uac00\ub2a5\ud55c \uc0dd\ubb3c\ud559 \ud45c\uc801\uc73c\ub85c \ubc14\ub77c\ubcf4\ub294 \uc2dc\uac01\uc740 \uc774\uc81c \uc2e4\ud5d8\uc2e4\uc744 \ub118\uc5b4 \uc784\uc0c1\uacfc \uc0b0\uc5c5\uacc4\ub85c \ud655\uc7a5\ub41c\ub2e4. \uc138\uacc4 \uc8fc\uc694 \uc81c\uc57d\uc0ac\uc640 \ubc14\uc774\uc624\ud14c\ud06c \uae30\uc5c5, \ud559\uacc4 \uc5f0\uad6c\uae30\uad00\ub4e4\uc774 \uad00\ub828 \uc5f0\uad6c\uc5d0 \ubc15\ucc28\ub97c \uac00\ud558\ub294 \uc911\uc774\ub2e4.<\/p>\n

\ub2f9\ub1e8\ubcd1 \uce58\ub8cc\uc81c \uba54\ud2b8\ud3ec\ub974\ubbfc(Metformin)\uc744 \ud65c\uc6a9\ud55c TAME \uc784\uc0c1\uc2dc\ud5d8(Targeting Aging with Metformin)\uc774 \ub300\ud45c\uc801\uc778 \uc2dc\ub3c4 \uac00\uc6b4\ub370 \ud558\ub098\ub2e4. \ubbf8\uad6d \ub0b4 65\uc138 \uc774\uc0c1 \uc131\uc778 \uc57d 3000\uba85\uc744 \ub300\uc0c1\uc73c\ub85c \uc124\uacc4\ud55c \uc774 \uc5f0\uad6c\ub294, \uba54\ud2b8\ud3ec\ub974\ubbfc\uc774 \ub178\ud654\uc640 \uad00\ub828\ud55c \ub9cc\uc131\uc9c8\ud658\uc758 \ubc1c\ubcd1\uc744 \uc9c0\uc5f0\uc2dc\ud0ac \uc218 \uc788\ub294\uc9c0\ub97c \ud3c9\uac00\ud55c\ub2e4. \ud2b9\uc815 \uc9c8\ud658\uc774 \uc544\ub2cc \u2018\ub178\ud654 \uc790\uccb4\u2019\ub97c \uc784\uc0c1 \uad00\ucc30 \uc9c0\ud45c\ub85c \uc124\uc815\ud588\ub2e4\ub294 \uc810\uc5d0\uc11c \uc758\ub8cc\uacc4\uc758 \uc8fc\ubaa9\uc744 \ubc1b\ub294\ub2e4.<\/p>\n

2022\ub144 \uacf5\uc2dd \ucd9c\ubc94\ud55c \ubc14\uc774\uc624\ud14c\ud06c \uae30\uc5c5 \uc54c\ud1a0\uc2a4\ub7a9\uc2a4\ub3c4 \ud559\uacc4\uc640 \uc5c5\uacc4\uc758 \uc2dc\uc120\uc744 \uc9d1\uc911\uc2dc\ucf30\ub2e4. \uc124\ub9bd \uc9c1\ud6c4 \uc57d 30\uc5b5 \ub2ec\ub7ec\uc758 \ucd08\uae30 \ud22c\uc790\uae08\uc744 \uc720\uce58\ud588\ub2e4. \uc81c\ud504 \ubca0\uc774\uc870\uc2a4\uac00 \ud22c\uc790\uc790\ub85c \ucc38\uc5ec\ud55c \uac83\uc73c\ub85c \uc54c\ub824\uc84c\ub2e4. \uc54c\ud1a0\uc2a4\ub7a9\uc2a4\ub294 \uc138\ud3ec \ub9ac\ud504\ub85c\uadf8\ub798\ubc0d \uae30\uc220\uc744 \ud1b5\ud574 \uc190\uc0c1\ub41c \uc138\ud3ec\uae30\ub2a5\uc744 \ubcf5\uad6c\ud558\uaca0\ub2e4\ub294 \ubaa9\ud45c\ub97c \ub0b4\uc138\uc6b4\ub2e4.<\/p>\n

\uc774\ub97c \uae30\ubc18\uc73c\ub85c \uc9c8\ubcd1\uacfc \ub178\ud654\ub85c\ubd80\ud130 \ud68c\ubcf5 \uac00\ub2a5\ud55c \uc0dd\ubb3c\ud559 \uc2dc\uc2a4\ud15c\uc744 \uad6c\ud604\ud558\uaca0\ub2e4\ub294 \uac83\uc774\ub2e4. \uc774\uc0ac\ud68c\uc640 \uc790\ubb38\ub2e8\uc5d0\ub294 \uc57c\ub9c8\ub098\uce74 \uad50\uc218\ub97c \ube44\ub86f\ud574 \ud6c4\uc131\uc720\uc804\ud559 \ubc0f \uc138\ud3ec \uc7ac\uc0dd\ubd84\uc57c\uc758 \uc804 \uc138\uacc4 \uc11d\ud559\uc774 \ud3ec\uc9c4\ud574 \uc788\ub2e4.<\/p>\n

\uc774 \uc678\uc5d0\ub3c4 \uce98\ub9ac\ucf54, \ub808\ud2b8\ub85c \ubc14\uc774\uc624\uc0ac\uc774\uc5b8\uc2a4, \uc720\ub2c8\ud2f0\ubc14\uc774\uc624\ud14c\ud06c\ub180\ub85c\uc9c0 \ub4f1 \ub2e4\uc591\ud55c \uae30\uc5c5\uc774 \ud65c\ubc1c\ud788 \ud65c\ub3d9\ud55c\ub2e4. \ub178\ud654 \uc138\ud3ec \uc81c\uac70, \ud154\ub85c\ubbf8\uc5b4 \uc5f0\uc7a5, NAD+ \uc218\uce58\ubcf5\uc6d0 \ub4f1 \ub178\ud654 \uc0dd\ubb3c\ud559\uc758 \uc5ec\ub7ec \uacbd\ub85c\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\ub294\ub2e4. \uc218\ubc31\ub9cc\uc5d0\uc11c \uc218\uc5b5 \ub2ec\ub7ec \uaddc\ubaa8\uc758 \ud22c\uc790\ub97c \uc720\uce58\ud558\uba70 \uc6c0\uc9c1\uc778\ub2e4.<\/p>\n

\uace0\uc815\ub41c \uc0b6\uc758 \ubc29\uc2dd \uc7ac\uad6c\uc131\ud560 \uc218\ub3c4<\/h3>\n

\ub178\ud654\uc5d0 \ub300\ud55c \uacfc\ud559\uc801 \uc811\uadfc\uc740 \uc0c8\ub85c\uc6b4 \uad6d\uba74\uc5d0 \uc811\uc5b4\ub4e4\uc5c8\ub2e4. \uc138\uacc4 \uacf3\uacf3\uc758 \uc5f0\uad6c\uc18c\uc640 \uae30\uc5c5\uc774 \uc138\ud3ec\uc758 \uc0dd\ubb3c\ud559 \uc2dc\uacc4\ub97c \ub418\uac10\uae30 \uc704\ud55c \ub2e4\uc591\ud55c \uc2dc\ub3c4\ub97c \ud558\ub294 \uc911\uc774\ub2e4. \uc544\uc9c1 \uac08 \uae38\uc740 \uba40\ub2e4. \ud558\uc9c0\ub9cc \uadf8\ub4e4\uc758 \uc2dc\ud589\ucc29\uc624\ub85c \u2018\ub299\ub294\ub2e4\ub294 \uac83\u2019\uc758 \uc815\uc758\ub294 \uc810\ucc28 \ub2ec\ub77c\uc9c8 \uac83\uc774\ub2e4.<\/p>\n

\uba38\uc9c0\uc54a\uc740 \ubbf8\ub798, \ubcd1\uc6d0\uc5d0\uc11c \uc0dd\ubb3c\ud559 \ub098\uc774\ub97c \uc9c4\ub2e8\ubc1b\uace0 \ub9de\ucda4\ud615 \ub178\ud654 \uac1c\uc785 \uce58\ub8cc\ub97c \uad8c\uc720\ubc1b\ub294 \uc77c\uc774 \uadf8\ub9ac \ub0af\uc124\uc9c0 \uc54a\uc744 \uc218\ub3c4 \uc788\ub2e4. \uad50\uc721, \ub178\ub3d9, \uc740\ud1f4, \ub178\ub144\uc774\ub77c\ub294 \uc775\uc219\ud55c \uc0b6\uc758 \uad6c\uc870\ub3c4 \uc810\ucc28 \ub2e4\ub978 \ubc29\uc2dd\uc73c\ub85c \uc7ac\uad6c\uc131\ub420 \uac00\ub2a5\uc131\uc774 \uc788\ub2e4.<\/p>\n

\ub178\ud654\uac00 \uc5b8\uc820\uac00 \uc9c8\ubcd1\ucc98\ub7fc \uc815\ubcf5\ub420\uc9c0, \uc544\ub2c8\uba74 \uc778\uac04 \uc874\uc7ac\uc758 \ubd88\uac00\ud53c\ud55c \uc77c\ubd80\ub85c \ub0a8\uc744\uc9c0\ub294 \uc544\uc9c1 \uc54c \uc218 \uc5c6\ub2e4. \uadf8\ub7ec\ub098 \uc9c0\uae08 \uc774 \uc21c\uac04\uc5d0\ub3c4 \uacfc\ud559\uc740 \ub178\ud654\ub77c\ub294 \uc624\ub798\ub41c \ud37c\uc990\uc744 \uc870\uae08\uc529 \ud480\uc5b4\uac04\ub2e4. \uadf8 \ub05d\uc5d0\ub294 \uc6b0\ub9ac\uac00 \uc544\uc9c1 \uc0c1\uc0c1\ud558\uc9c0 \ubabb\ud55c \uc0b6\uc758 \ud615\ud0dc\uac00 \uae30\ub2e4\ub9ac\uace0 \uc788\uc744\uc9c0\ub3c4 \ubaa8\ub978\ub2e4.<\/p>\n","protected":false},"excerpt":{"rendered":"

\ubaa8\ub4e0 \uc774\uac00 \ub299\ub294\ub2e4\ub294 \uc6b4\uba85\ub860\uc740 \uc61b\ub9d0\uc774\ub2e4. \ub178\ud654\ub97c \uc5ed\ud589\ud558\uace0, \uc80a\uc74c\uc744 \ub3c8\uc73c\ub85c \uc0b4 \uc218 \uc788\ub2e4\ub294 \uac00\ub2a5\uc131\uc774 \uc5b8\uae09\ub418\uba74\uc11c \uc778\ub958\uc758 \uc0c1\uc2dd\uc744 \ub4a4\uc5ce\uc5c8\ub2e4. \u24d2 shutterstock \uc80a\uc74c\uc744 \ud5a5\ud55c \uac08\ub9dd\uacfc \ub178\ud654\uc5d0 \ub300\ud55c \uacf5\ud3ec. \uc740\ud1f4\ud55c 50\uc138 \uc804\uc9c1 \uc2a4\ud0c0\uac00 \uc2e0\ube44\ub85c\uc6b4 \uc2e0\uc57d\uc73c\ub85c \uc80a\uc74c\uc744 \ub418\ucc3e\ub294\ub2e4. \uc601\ud654 <\uc11c\ube0c\uc2a4\ud134\uc2a4>\ub294 \uc778\uac04\uc758 \uac00\uc7a5 \uc6d0\ucd08\uc801\uc778 \uc695\ub9dd\uc744 \uadf8\ub85c\ud14c\uc2a4\ud06c\ud558\uac8c \ud480\uc5b4\ub0b8\ub2e4. \ubb3c\ub860 \uc774\uc57c\uae30\ub294 \uc601\ud654\uc801 \ud5c8\uad6c\ub2e4. \ud558\uc9c0\ub9cc \uc601\ud654\uac00 \ub358\uc9c0\ub294 \uc9c8\ubb38\uc740 \ub354 \uc774\uc0c1 \uacf5\uc0c1 \uacfc\ud559 \uc601\uc5ed\uc5d0\ub9cc \uba38\ubb3c\uc9c0 […]<\/p>\n","protected":false},"author":181,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2315","post","type-post","status-publish","format-standard","hentry","category-1"],"_links":{"self":[{"href":"https:\/\/beyondlife.kr\/index.php?rest_route=\/wp\/v2\/posts\/2315","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/beyondlife.kr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/beyondlife.kr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/beyondlife.kr\/index.php?rest_route=\/wp\/v2\/users\/181"}],"replies":[{"embeddable":true,"href":"https:\/\/beyondlife.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2315"}],"version-history":[{"count":1,"href":"https:\/\/beyondlife.kr\/index.php?rest_route=\/wp\/v2\/posts\/2315\/revisions"}],"predecessor-version":[{"id":2316,"href":"https:\/\/beyondlife.kr\/index.php?rest_route=\/wp\/v2\/posts\/2315\/revisions\/2316"}],"wp:attachment":[{"href":"https:\/\/beyondlife.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2315"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/beyondlife.kr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2315"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/beyondlife.kr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2315"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}